I have shot handguns with lasers and RDS, but don't own any.
Regarding lasers, from experience with friend's guns, be wary of cheapos. They don't seem to hold zero, if you can get them zero'ed at all. It also helps to have an indoor range and targets that you can set up closer, like say 5-7 yards to get a "decent" zero. Trying to zero the laser at the 25 yard targets at Koko Head and in the bright sun can be a royal PITA.
One thing I often wondered about with lasers is what distances they are effective at, or where they add "value" to having them. I would think in the 5 yards to maybe up to even 10 yards range. Beyond that, I've noticed that the laser dances around a lot. Closer, I don't envision many (or anyone) really using their sights.
Another aspect was turning the laser on under stress. I've played with the Crimson Trace type ones that have the pressure pad on the grip, but I wondered how it really works when under stress. I've shot with my handgun with light and even that takes some practice to get used to.
Maybe one of these days I'll get one to try. But for now, I haven't felt the need to spend the money and try.