How would you compare shooting the Casull and other less common caliber/handguns to the popular, widely available calibers/ handguns like the 357 mag, 44 mag or special etc.?
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Just remember when I answer you the Casull, 500, 480 and 460 has to be shot from an extra large frame and heavy revolver. While the .44 and .357 Magnums that I regularly shoot are from S&W N Frames which is a large heavy frame but no where as large as the Ruger Super Redhawk and S&W X- Frame. So it is different to shoot the different cartridges.
I hated the Ruger Super Redhawk not realizing the grips were the real problem I replaced the originals with some Hogue Recoil Tamers. They make all the difference in the world for me. Not because they help with the recoil but just being able to handle the gun and recoil better with more control. The original grips allowed the gun to move/rotate in my hand. Not so with the Hogue grips. I am a big fan of less popular cartridges. Because of my friends I get to shoot .41 Special and Magnums as well as .44 Special and Magnums. I have also shot the S&W 500 Magnum and well as the .460 and Ruger .480 through friends. While the S&W 500 Magnum is the most recoil I have ever felt, the .454 Casull is not far behind it. However, with the Hogue grips I can actually control the gun even with the heavy recoil. After those I think the .460 and .480 are closer to the .44 Magnum. Just remember I shot those through a S&W X-Frame. I am not a big fan of the .44 Magnum. The N Frame seems a little small/light for the cartridge. I cannot control it as easily as the Casull. But again don't forget the size and weight of the guns are very different. Also, the N Frame I usually shoot has stock wood grips. It would certainly be better with good rubber grips. I think my favorite out of all the magnum cartridges mentioned above is the .41 Magnum. Mostly because it is an oddball I think.
The .41 and .44 Specials are both a pleasure to shoot. Rimmed cartridges in revolvers are a must for me these days. I have had enough of moon and half moon clips. So these are a lot of fun to shoot for me. It is great to push a big old slug out the barrel with authority and still have control over the gun. With all this said, my favorite revolver cartridges are the .45 Colt (sometimes called the Long Colt) and the .38/.357 Magnum. The .357 is probably the best compromise between good stopping power and gun recoil/gun control. The nice thing about the .357 is you have so much of a selection in bullet weights and powder charges you can shoot mild target loads all the way up to some pretty hot loads. Even really hot .357 Magnum loads are pretty controllable. But between the 2 of these the .45 Colt is my favorite. The variety of weight of projectile and powder charges is amazing. I can load everything from cowboy loads to more powerful than .44 Magnum loads. So the fun of shooting loads similar to the Specials mentioned above combined with a cartridge case designed over 100 years ago that can withstand loads almost as great as a Casull load is my idea of fun shooting. Plus I have a black powder gun I shoot black powder loads with the same cartridge.
I have also shot the S&W .500 Magnum from a lever gun. It is a brute of a cartridge from a lever action carbine. You can imagine what it is like in a revolver. The .45 Colt and .357/.38 are a joy to shoot from lever guns.
As I get older I get more adverse to recoil. I find myself loading less and less hot loads for my guns. My pet loads for the .45 Colt is not quite a bunny fart or cowboy load. But not up to the recoil of a .357 Magnum. My favorite .357 Magnum load is in the realm of the .38 Special +P velocity. I have recently been developing loads for a S&W 25 which is .45 ACP. It is an N frame with stock wood grips and I got rimmed cases for it. I am developing a load for it currently.
I hope this has answered your question.