If you are using optics with no magnification such as Aimpoints, Eotechs, C-more red dots, etc, you can get your back up iron sights to "co-witness."
This means you can still index your irons through the glass of the red dot sight. All of these optics mentioned are battery powered. What this means is your battery can go out, internal electronics can get damaged or short out, or just plain stop working from banging around or constant recoil. When this happens you need iron sights to continue. This ofcourse is an issue for our men and women in battle as well as our law enforcement. For most people like us, we have the luxury of taking a break to insert new batteries, order new optics when they fail, or simply pack up from the range and go home. If you ask most military personnel they will tell you the shit fails when you need it most, at that point your back up irons are a life saver. The other malfunction you may encounter with optics is if your glass breaks.
Aimpoints are the most reliable, Eotech's reticle is useful, however no where near as reliable as an Aimpoint. Also Aimpoints generally have better battery life than Eotechs. Depending on the model, some aimpoints can go 50,000 hours on mid level dot intensity. I personally have never had an Aimpoint go out on me. I am also not in the desert day in and day out, banging my rifle around, clearing houses, diving for cover, and much less returning fire constantly. But from a personal preference Aimpoints are all I run.