Any trouble picking up the dot or notice any lag in shooting over irons?
What distance(s) and what time(s) you looking for? Personally, in general no. If anything, I would say I need more time shooting irons again.
There are a bunch of videos on red dot slower than irons. I experienced that intially and is very common. There are a few (at least) schools of thought. At least from classes I took, training with friends, videos.
First is concept of index. Where repetition and put the dot where your eyes are focused. One main reason I've consolidated to primarily shooting Glock. I still have Sig, CZ, etc, but rarely shoot them. Messes me up, at least temporarily. There are many that can adjust with say minutes of dry draw/fire, but I can't. . . at least not yet.
Second is gross sight picture or acceptable confirmation. Are you trying to get the same level of target confirmation with your RDS at various distances? Are you truly doing that with irons? Or is say more "quick and dirty" sight pictures acceptable? Say at 3-5 yards. Backplate of gun, RDS window, top "line" of the optic body, etc. I read that there are courses dedicated to shooting with NO RDS or irons, but haven't seen videos or read/watched feedback from those who have taken those courses. Not saying that's good or bad, but interesting to at least test for my/ones self.