read lots of reloading books/manual...pay serious attention to the warnings and safety cautions....do not double charge, or go over the max recommended load, start at the minimum or middle of the recommended load (and test it on your gun), watch for signs of pressure when test firing your loads (stop, if there are signs of pressure, ie.really flattened primers, punctured primers, blown cases, etc), do not mix powders, concentrate (do not get distracted), do it slow and cautious at first, double check, check powder level occasionally, pistol powder is for pistol loads, and rifle powder is for rifle loads (there are exceptions, but that's advance level), somebody else's load might not work on your gun,.... be safe