I keep reading posts from reloaders in this forum and other that say they've found some magic combo of powder, lube (not powder coat) and cast boolits that do not cause barrel leading. I've been shooting cast boolits for years and have yet to find a combo that doesn't result in some amount of barrel leading. Perhaps, I'm just not doing it right but I'm really beginning to think that shooting lead without getting leading is as rare and having farts that don't stink.
Can any of you truly say that you've experienced no leading with a certain combo of powder, lube and bullet or are you really just saying 1) I think i'm not getting any leading but I'm too afraid to check; 2) I haven't been getting any leading when swabbing my barrel with cotton balls instead of Chore Boys Scouring Pads; or 3) I get small kine leading but not as thick as the pancake mix-like cosmetic on my mother in-laws face that I used to get?
Before I answer you I have to say even when you get to the point of no leading, there are always going to be small tiny flecks of lead on your first, maybe second patch when cleaning. I have experienced leading to the point it filled in the grooves of my .357 revolver. It took over an hour of scrubbing with a bronze brush to remove all the lead. And this happened while using the correct powder, charge, lube, etc.
While I am no expert I will just give you my experience. I don't cast my own. But for me the key is hardness and powder choice along with velocity choice (with or without gas checks). For hardness decisions I will defer to the experts like Old Fart or Old Mose. I buy my lead heads from a local source which casts some very hard bullets in the range of Brinnell 16-18. Which is pretty hard. He also has his own lube recipe. One more thing I consider is boolit diameter. He swages the boolits to my specs for my particular guns. It works well in everything I shoot from bunny fart pistol loads to bunny fart rifle loads to semi hot rifle loads to extremely hot pistol loads. But I think powder choice, velocity, gas check or no gas check and lube is important. So assuming I am going to buy a hard cast bullet with good lube, I then have to decide what velocity I intend to push it to. I found pushing lead boolits in pistols to about 900 fps in a pistol can be done successfully without a gas check. Over 900fps to 1,000 I may or may not use a gas check. Over 1,000fps I always use a gas check. And in my 45 Colt loads I push 300gr lead with gas check well past 1,200fps into the .454 Casull range. No leading. I shoot 38/357 lead with no gas checks from 750fps to around 1,000fps.
For rifle rounds I always use a gas check even with a load I shoot for my Mosin nagant in the 1,400fps range. I could proabably get away with no gas check up to about 1,700 or 1,800fps but why even bother when the cost of lead boolits with gas check are only a penny or two more. I load up to about 2,100 to 2,200fps. After that lead boolits seem to become unstable in my rifles/applications.
For powder choices there are some that are particularly good with lead boolits. For pistols I use Titegroup, Bullseye, IMR Target, Unique and there are tons of others. For rifles I use H4895, IMR 4895, IMR 4064 and my favorite IMR 4198. I have tried with H335 with limited success.
There are a lot of powders that work well with lead boolits. To find out which powders work well, and for getting some good load data I recommend you get the Lyman Cast Bullet Manual. If you have the 49th edition of the Lyman manual you probably have about 75% of the load data in there. But I like the Lead manual as I don't have to look past the jacketed load data and I only have to concentrate on velocity and powder/charge.
There are many other items to consider but the Lyman manual pretty much covers everything you will need to know.